Tricarboxylic acids and derivatives
Medchemexpress LLC Citrate synthase | 9027-96-7 | MFCD00131495 | ~98 KDa dimer | 250 U
Citrate synthase catalyzes the first reaction of the citric acid cycle, condensing acetyl-CoA and oxaloacetate to form citrate. This enzyme is localized within eukaryotic cells in the mitochondrial matrix.
- Catalyzes the first reaction of the citric acid cycle
- Condenses acetyl-CoA and oxaloacetate to form citrate
- Localized in the mitochondrial matrix
- Specific activity: ≥100 U/mg protein
- Appearance: Colorless to light yellow liquid
- Source: Microorganism
Apexbio Technology LLC Enclomiphene citrate 7599-79-3 5mg
Enclomiphene citrate (CAS 7599-79-3) is a small-molecule antagonist targeting estrogen receptors It is designed to competitively bind to estrogen receptors thereby inhibiting receptor-mediated estrogen signaling and attenuating estrogen-induced negative feedback on the hypothalamic-pituitary axis Enclomiphene citrate exerts its biological activity primarily by increasing endogenous secretion of gonadotropins including luteinizing hormone (LH) and follicle stimulating hormone (FSH) which promotes endogenous testosterone biosynthesis in gonadal tissues Based on these pharmacological properties enclomiphene citrate holds research potential in studies of male hypogonadism fertility disorders and regulation of male gonadal function
Selleck Chemical LLC Oxacillin sodium monohydrate S2563-50mg
Oxacillin sodium monohydrate (Methicillin) is an antibacterial agent and is a narrow spectrum beta-lactam antibiotic of the penicillin class
Medchemexpress LLC (E/Z)-Zotiraciclib hydrochloride | 1321626-25-8 | C23H25ClN4O | 5 MG
(E/Z)-Zotiraciclib ((E/Z)-TG02) is an orally active inhibitor of CDK2, JAK2, and FLT3 with IC50s of 13, 73, and 56 nM, respectively. It effectively inhibits the proliferation of cancer cells, making it suitable for cancer research.
- Orally active inhibitor of CDK2, JAK2, and FLT3
- Inhibits proliferation of cancer cells
- Useful for cancer research
- Potently inhibits the CDK2 biomarker pRb
Selleck Chemical LLC Ibandronate sodium monohydrate S3148-1g
Ibandronate (BM-21 0955 BM-210955 RPR-102289A) is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis
Alkali Scientific L (+) Rhamnose, Monohydrate, 5 Kg
L (+) Rhamnose Monohydrate, 5 kilograms, is a bulk quantity of this high-purity sugar used in large-scale laboratory experiments, especially in studies involving microbiology and plant metabolism. This form of rhamnose is essential for fermentation processes, bacterial growth studies, and enzyme assays that require a consistent and controlled sugar source. The 5kg quantity is ideal for extensive research applications, supporting high-throughput testing and long-term experiments. Rhamnose plays a critical role in the study of cell wall biosynthesis, bacterial metabolism, and microbial enzymatic activity, offering reliable results in biochemical and environmental testing protocols.
![Alkali Scientific Sodium Citrate, Trisodium Salt, Dihydrate, [Citric Acid, Trisodium Dihydrate], 1 Kg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000660960.jpg-250.jpg)
Alkali Scientific Sodium Citrate, Trisodium Salt, Dihydrate, [Citric Acid, Trisodium Dihydrate], 1 Kg
Sodium Citrate, Trisodium Salt, Dihydrate, laboratory grade, is commonly used in buffer preparation and other laboratory applications. This 1 kg package of trisodium citrate dihydrate is a versatile reagent that plays a critical role in maintaining pH balance during chemical and biological experiments. Sodium citrate is widely used in the preparation of anticoagulants for blood samples, in the formulation of buffers for molecular biology applications, and in various enzymatic assays. The trisodium salt form of citrate ensures effective buffering capabilities, maintaining stability across a broad range of pH values. This reagent is ideal for use in biochemical research and laboratory settings that require precise pH control.
Medchemexpress LLC Adenosine 5'-(α,β-methylene) diphosphate (triammonium) | 99.9% | 476.32 | 25 MG
MethADP (Adenosine 5'-(α,β-methylene)diphosphate) triammonium is a CD73 inhibitor that can be used for research of the ATP-adenosine pathway.
- CD73 inhibitor.
- Can be used for the research of the ATP-adenosine pathway.
- Inhibits 5'-AMP induced adenosine formation in A498 cells (in vitro).
Medchemexpress LLC Bragsin1 | 369631-68-5 | 99.9% | 273.16 | 10 MG
Bragsin1 is a potent, selective, and noncompetitive inhibitor of the ArfGEF BRAG2, which inhibits Arf GTPase activation with an IC50 of 3 μM. It functions as a noncompetitive interfacial inhibitor by binding to the PH domain of BRAG2 and does not affect the Sec7 domain of human ArfGEFs. Bragsin1 also exhibits anti-cancer activity.
- Potent, selective, and noncompetitive inhibitor of ArfGEF BRAG2.
- Inhibits Arf GTPase activation with an IC50 of 3 μM.
- Binds to the PH domain of BRAG2.
- No effect on the Sec7 domain of human ArfGEFs.
- Exhibits anti-cancer activity.
Medchemexpress LLC Methadp triammonium (adenosine 5'-(α,β-methylene)diphosphate triammonium) | 99.9% | 476.32 | 100 MG
MethADP (Adenosine 5'-(α,β-methylene)diphosphate) triammonium is a CD73 inhibitor. It can be used for the research of ATP-adenosine pathway.
- Acts as a CD73 inhibitor
- Used for research of the ATP-adenosine pathway
- Inhibits 5'-AMP induced adenosine formation in A498 cells
Medchemexpress LLC Boc-NH-PEG2-CH2COOH | 108466-89-3 | 263.29 | 100 G
Boc-NH-PEG2-CH2COOH is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are designed with two different ligands connected by a linker; one binds to an E3 ubiquitin ligase and the other to the target protein, enabling the selective degradation of target proteins through the intracellular ubiquitin-proteasome system.
- Peg-based protac linker
- Used in the synthesis of protacs
- Enables selective degradation of target proteins
Selleck Chemical LLC Edoxaban tosylate Monohydrate
Edoxaban (DU-176b) is a selective factor Xa inhibitor with Ki of 0 561 nM 10 000-fold selectivity over thrombin and FIXa and is also an orally bioavailable anticoagulant drug